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Goitre

       Definition
A goitre is a swelling in the neck due to an enlarged thyroid gland.

       Classification

       A "diffuse goitre" is a goitre that involves the whole of thyroid
       Simple goitre - uniform enlargement
       Multinodular goitre - muliple nodules +
       Toxic goitre =  goitre with hyperthyroidism.
       Usually due to Graves disease
       Can be caused by inflammation or a multinodular goitre.
       Nontoxic goitre  -  with normal or low thyroid levels

        Causes
       Hashimoto's thyroiditis        
       Thyroiditis - viral infection
       Graves disease
       Inborn errors of thyroid hormone synthesis, causing congenital hypothyroidism        
       Side-effects of pharmacological therapy
       Thyroid cancer
       Iodine deficiency
Goitre is more common in women

       Treatment
       Small goitre - may be physiological - may not need any treatment.
       If due to hypothyroidism- treated with eltroxin -  leads to a substantial reduction in the size of the goitre.
       If it causes difficulty with breathing or swallowing  -  surgery
       Radioiodine therapy
       Thyroidectomy
       Thyroiditis with goitre - antiinflammatory drugs - steroids - anti virals - sterioids - later may need                thyroxine supplementary



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                  by
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Please use the above e-mail address kasiviswanathanvatyahoodotcom for any suggestions for improvements. Please feel free to communicate any of your requirements.
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